Description
Laboratory Research Technician
Med-Ophthalmology - Pennsylvania-Pittsburgh - (25006800)
A Research Tech II position is available in the Visual Function and Rehabilitation lab of the University of Pittsburgh, Ophthalmology Department. The research will focus on developing methods for visual rehabilitation following treatment of inherited retinal disorders under the supervision of Dr Boris Rosin MD, PhD at the University of Pittsburgh Department of Ophthalmology (Vision Institute). The Visual Function and Rehabilitation Lab deals with the processing of the visual signal in the Central Nervous System (CNS). We explore changes to the visual pathways of the CNS during the development of visual impairment and after treatment. Some of the disease systems are murine models of Inherited Retinal Dystrophies (IRDs), traumatic optic neuropathy and amblyopia. We are specifically interested in preventing visual pathway "rewiring" during the development of visual disability as a means to improve treatment outcome. Techniques include multi-electrode array electrophysiological recordings, behavioral essays, visual acuity and function testing in rodents. Future non-human primate work is planned. The lab has a close collaboration with the molecular biology lab within the Department to specifically examine the CNS changes prior and after application of gene therapy for the treatment of IRDs.
Research at the Vision Institute is a comprehensive effort to address all aspects of visual disability. This includes multiple basic science disciplines such as embryology, molecular biology, material science and others. There is a close collaboration with the clinical side of the Department, with multiple interactions with physicians assuring relevance of the scientific questions posed.
Job Summary
Performs a variety of laboratory experiments and procedures. Prepares specimens. Oversees supply management. Operates and properly maintains equipment.
Essential Functions
The Research Tech will be engaged in performance of approved research projects according to defined and newly established protocols and procedures. These include the appropriate collection, recording, storage, data analysis, and reporting of results. Laboratory procedures and techniques include handling of murine models (rats and mice) and routine maintenance of colonies, electrode array implantation surgery, gene therapy application, training and handling of animals performing behavioral tasks, extraction and analysis of nucleic acids (RNA, DNA) by qPCR, basic microscopy and genotyping. Other routines include preparation of reagents, calibration of equipment for research projects, collaborative efforts with other laboratories employing molecular biology techniques and maintenance of a safe laboratory-working environment.
Physical Effort
This is a standard laboratory position. Must be able to perform some physical labor (e.g. pushing an equipment cart, light lifting) and work with animals.
Assignment Category: Full-time regular
Job Classification: Staff.Laboratory Research Technician II
Job Family: Research
Job Sub Family: Laboratory
Campus: Pittsburgh
Minimum Education Level Required: Bachelor's Degree
Minimum Years of Experience Required: 1
Will this position accept substitution in lieu of education or experience: Combination of education and relevant experience will be considered in lieu of education and/ or experience requirement.
Work Schedule: M- F 8:30am to 5:00pm
Work Arrangement: On-Campus: Teams that work on campus, in an office, or in a lab.
Hiring Range: TBD Based Upon Qualifications
Relocation_Offered: No
Visa Sponsorship Provided: No
Background Check: For position finalists, employment with the University will require successful completion of a background check
Child Protection Clearances: Not Applicable
Required Documents: Resume
Optional Documents: Cover Letter
PI280501748